[ad_1]
WASHINGTON, Oct. 13 (PTI) — Risk factors for cardiovascular disease, such as obesity, smoking and diabetes, but not pre-existing heart disease, are major contributors to death and poor outcomes in severely ill COVID-19 patients, according to a study.
Mortality rates in patients with cardiovascular disease were nearly 30% higher than in severely ill COVID patients without pre-existing conditions. However, this relationship was no longer statistically significant when adjusted for risk factors including age, sex, race, smoking, etc.
Also read | Rape in Pakistan: A woman is sexually assaulted every two hours, reports say.
“The fact that the association between cardiovascular disease and death was substantially reduced when comorbidities were considered, suggests that cardiovascular risk factors, rather than pre-existing heart disease, are the leading cause of in-hospital mortality in critically ill COVID-19 patients,” senior The author says Salim Hayek.
The team, led by researchers at the University of Michigan, analyzed outcomes from more than 5,100 critically ill COVID patients admitted to intensive care units at 68 U.S. centers between March and June 2020.
Also read | India has lashed out at Pakistan after the UN General Assembly vote on Ukraine angered the Kashmir issue.
Of these patients, 1,174 had previous coronary artery disease, congestive heart failure, or atrial fibrillation.
A total of 34.6% of patients died within 28 days, and nearly 18% had a cardiovascular event, such as cardiac arrest or myocarditis.
The association between such events and death did not differ between patients with and without heart disease, the researchers said.
The study, published in the journal Circulation: Cardiovascular Quality and Outcomes, found myocardial damage was associated with cardiovascular events and death, regardless of whether patients had heart disease.
In ICU patients, myocardial injury is common, with nearly half having elevated levels of troponin, a protein released when the heart muscle is damaged.
Patients with the highest troponin measurements were nearly three times more likely to die than those without myocardial damage, the researchers said in a statement.
“While severe COVID patients often have signs of cardiac damage, our findings reinforce COVID-19 as a lung disease with multiple organ damage associated with systemic inflammation,” Hayek said.
“The evidence of heart damage that we often see in severely ill COVID-19 patients is more likely to reflect the severity of the disease and the stress it places on all organs, rather than the development of new complications or deterioration of the original heart,” he said. Say.
The findings should not minimize the fact that patients with cardiovascular disease are still at risk of dying from COVID-19 because they have a high burden of disease risk factors, such as diabetes, hypertension, said co-first authors. And smoking Alexis Wasbender.
“We are currently conducting studies to further identify the COVID-19 patient population at highest risk for serious outcomes, such as those with advanced heart failure or coronary artery disease,” Vasbinder said.
Cardiovascular disease is a common disease in patients with severe COVID-19 disease, given its prevalence and associated chronic inflammation in older adults.
In this study, age, obesity and diabetes were stronger predictors of death from COVID, the researchers added.
(This is an unedited and auto-generated story from the Syndicated News feed, the body of the content may not have been modified or edited by LatestLY staff)
[ad_2]
Source link